The Herb Cabinet 本草
泽泻 zé xiè
Alisma orientale · water plantain rhizome
“The marsh plant that teaches water where to go. Every rich tonic formula needs a drain — this is the one Liu Wei Di Huang Wan trusts.”
— Lao Xinglin
What the tradition says
A marsh plant for marsh problems: ze xie promotes urination and drains dampness, with a cold edge that also clears the murky heat dampness breeds — difficult or burning urination, edema, damp-heat below[1]. Its most instructive job is in Liu Wei Di Huang Wan: as rehmannia floods the kidney with rich yin, ze xie flushes the turbidity such richness creates — the tradition's three-fill-three-drain architecture depending on a drain this reliable[1]. It also appears wherever phlegm-fluids collect: the classic pair with bai zhu treats dizziness from fluids misting upward.
What the research says
Alisma triterpenes are studied for diuretic and lipid-lowering signals in animal models; human evidence is thin and mostly formula-bound. One real note from the pharmacovigilance literature: very high, prolonged doses have raised concern in animal studies — another argument for formula doses over supplement enthusiasm.
Where to be careful
A cold drainer is wrong for the depleted-and-dry: the tradition withholds it where yin deficiency shows without dampness, and in leaking-essence patterns[1]. Not an herb for daily solo use.
In the pharmacy
Cream-white, dense rounds of Alisma orientale rhizome. Salt-fried ze xie aims the drain more squarely at the kidney[1].
References
- Bensky, Clavey & Stöger, Chinese Herbal Medicine: Materia Medica, 3rd ed., Eastland Press, 2004. ↩
Formulas that use it
Reviewed 2026-08-26